Retatrutide Reconstitution
Specialized calculator for the GIP/GLP-1/Glucagon receptor agonist (LY3437943). Investigational use only.
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Mixing Parameters
Required Target Dose (Retatrutide)
Draw the liquid to the mark on your syringe.
Retatrutide Calculation Breakdown
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01
Retatrutide Vial (mg) converts to:
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02
Mixed with mL bacteriostatic water creates: solution
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03
To get mcg, you need units on the syringe.
Understanding Retatrutide (LY3437943)
Retatrutide is a novel investigational peptide that acts as a triple agonist, targeting the receptors for GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and Glucagon. This "Triple G" mechanism is currently being studied for its potential in significant weight management and metabolic health improvement.
Research Use Only: Retatrutide is an investigational compound not yet approved by the FDA. The information below reflects protocols observed in clinical studies (e.g., TRIUMPH-1) and is for educational research purposes only.
Common Research Titration Schedule
Clinical trials typically follow a monthly escalation schedule to mitigate gastrointestinal side effects.
| Phase | Weekly Dose | Duration |
|---|---|---|
| Initiation | 2 mg | 4 Weeks |
| Step 1 | 4 mg | 4 Weeks |
| Step 2 | 8 mg | 4 Weeks |
| Maintenance (Max) | 12 mg | Indefinite |
Stability & Storage
- ✓ Reconstituted: Stable for 3-4 weeks when stored at 2°C to 8°C (Refrigerator). Do not freeze after mixing.
- ✓ Lyophilized (Powder): Stable for up to 2 years at -20°C (Freezer).
Retatrutide 10mg Reconstitution Chart
Based on standard 10mg Vial + 2mL Bacteriostatic Water
| Desired Dose | Unit Pull (U-100) | mL Volume |
|---|---|---|
| 1 mg (1000 mcg) | 20 Units | 0.20 mL |
| 2 mg (2000 mcg) | 40 Units | 0.40 mL |
| 4 mg (4000 mcg) | 80 Units | 0.80 mL |
| 8 mg (8000 mcg) | 160 Units (1.6 syringes) | 1.60 mL |
