Veterinary Sedative Calculator

Trazodone for Dogs

Calculate weight-based Trazodone dosages for canine anxiety, travel stress, and post-surgical sedation. Standard veterinary range: 2-7 mg/kg.

Standard Range

2-7mg/kg

Every 8-24 hours as needed

Dosage Calculator

Dog's Weight

= kg

Anxiety Level / Indication

Tablet Strength

Important: Trazodone is a prescription medication. Always consult your veterinarian before administering. May cause sedation, GI upset, or behavioral changes.

Calculated Dose

Trazodone Dosage

For

Target Dose

Administration

of mg tablet

Safe Range for This Weight

Minimum

Maximum

⏰

Timing

1-2 hrs before event

🍽️

With Food

Reduces GI upset

🔁

Frequency

Every 8-24 hours

Trazodone Dosage Reference Chart

Quick reference for common dog weights at standard (3-5 mg/kg) dosing

Dog Weight	Low Dose (2 mg/kg)	Standard (4 mg/kg)	High (7 mg/kg)
10 lbs (4.5 kg)	9 mg	18 mg	32 mg
20 lbs (9 kg)	18 mg	36 mg	63 mg
30 lbs (13.6 kg)	27 mg	54 mg	95 mg
50 lbs (22.7 kg)	45 mg	91 mg	159 mg
70 lbs (31.8 kg)	64 mg	127 mg	222 mg
100 lbs (45.4 kg)	91 mg	181 mg	318 mg

Understanding Trazodone for Dogs

💊 What is Trazodone?

Trazodone is a serotonin antagonist and reuptake inhibitor (SARI) commonly prescribed by veterinarians for anxiety management in dogs. It works by increasing serotonin levels in the brain, producing calming and mild sedative effects.

🎯 Common Uses

• Travel and car anxiety
• Thunderstorm/firework phobias
• Post-surgical crate rest
• Veterinary visit anxiety
• Separation anxiety

⚠️ Important Safety Information

Side Effects

• Sedation and drowsiness
• GI upset (vomiting, diarrhea)
• Ataxia (wobbly gait)
• Increased anxiety (paradoxical)

Contraindications

• Should not combine with MAOIs
• Use caution with other serotonergic drugs
• Avoid in dogs with severe liver disease
• May interact with certain heart medications

Frequently Asked Questions

Trazodone typically begins working within 1-2 hours of administration. For best results with situational anxiety (like travel or vet visits), give the medication 1-2 hours before the anticipated stressful event.

Yes, Trazodone can be used daily under veterinary supervision for dogs with chronic anxiety. Many vets prescribe it as a daily medication alongside behavior modification programs. Always follow your vet's specific dosing schedule.

No, they are different medications. Trazodone is a SARI (serotonin antagonist and reuptake inhibitor), while Xanax (alprazolam) is a benzodiazepine. Both can reduce anxiety, but they work through different mechanisms. Trazodone is often preferred for its wider safety margin.

Clinical Review

Reviewed by Dr. Igor I. Bussel, MD

Board-Certified Ophthalmologist

Last Updated: December 28, 2024

Sources & Guidelines

• Plumb's Veterinary Drug Handbook (9th Ed.)
• AAHA Canine Anxiety Guidelines
• Merck Veterinary Manual