VETERINARY USE ONLY: THIS TOOL IS FOR INFORMATIONAL MATH. ALWAYS CONFIRM DOSAGES WITH A LICENSED VETERINARIAN.
Feline Health Protocols

Feline Dosage Guidelines

Essential safety information for cats. Understanding unique metabolic constraints and strictly prohibited substances.

🐈 "Cats are NOT Small Dogs"

This veterinary adage is the #1 rule of feline medicine. Cats possess a unique liver metabolism that makes them incapable of processing certain compounds that are safe for humans and dogs.

Glucuronidation Deficiency

Cats lack specific enzymes (glucuronyl transferases) needed to break down certain drugs. This means these drugs can build up to fatal toxic levels very quickly.

⛔ NEVER ADMINISTER TO CATS ⛔
  • Acetaminophen (Tylenol/Paracetamol)
  • Even a tiny crumb can kill a cat. Causes methemoglobinemia (suffocation from within) and liver failure.
  • Permethrin (Dog Flea Medication)
  • Highly toxic to cats. Never use dog flea products on cats or even allow a cat to groom a treated dog.
  • Ibuprofen & Aspirin
  • Cats are extremely sensitive to NSAIDs. Only use vet-prescribed feline-specific NSAIDs (e.g., Onsior, Meloxicam w/ caution).
  • Common Safe Medications

    Note: Always consult a vet for dosage. These are general reference compounds.

    Prednisolone

    The preferred steroid for cats. Cats cannot efficiently convert Prednisone to Prednisolone in the liver, so Prednisolone must be prescribed directly.

    Gapapentin

    Widely used for stress reduction (vet visits), pain management, and sedation. Very safe profile but causes ataxia (wobbly walking).

    Amoxicillin / Clavamox

    Generally well-tolerate liquid antibiotics. Often flavored, but cats may still foam at the mouth due to taste (not necessarily toxicity).

    Buprenorphine

    An opioid pain reliever often given transmucosally (absorbed through gums), making it easier to administer than pills.

    Success Strategies for Pills & Liquids

    1

    Burrito Technique: Wrap the cat snugly in a towel to control claws.

    2

    Liquid meds: Aim for the side of the mouth (cheek pouch), never straight down the throat to avoid aspiration.

    3

    Pill Pockets: Soft treats that hide pills work for 70% of cats. Do not touch the outside of the treat with "medicine fingers".

    Clinical Review
    Dr. Igor I. Bussel
    Dr. Igor I. Bussel, MD
    Board-Certified Ophthalmologist

    Dr. Igor I. Bussel is a board-certified ophthalmologist and fellowship-trained surgeon affiliated with the University of California, Irvine (UCI), the Gavin Herbert Eye Institute, and the UCI School of Medicine.

    Last Updated: January 2026
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