How often should I give my dog Zyrtec?

Zyrtec is typically given once daily. It can be given with or without food. For best results with seasonal allergies, give it consistently at the same time each day.

Is Zyrtec better than Benadryl for dogs?

Zyrtec (cetirizine) is a second-generation antihistamine that causes less drowsiness than Benadryl (diphenhydramine) and only needs to be given once daily instead of 2-3 times. However, some dogs respond better to one or the other.

What are the side effects of Zyrtec in dogs?

Side effects are uncommon but may include mild drowsiness, drooling, or vomiting. Cetirizine is generally well-tolerated by dogs. If you notice any concerning symptoms, contact your veterinarian.

Can I give Zyrtec with other allergy medications?

Zyrtec can often be combined with other allergy treatments like Apoquel or Cytopoint under veterinary guidance. Do not combine with other antihistamines without consulting your vet.

Veterinary+ Chart

Zyrtec (Cetirizine) Dosage Calculator for Dogs

Calculate the correct Zyrtec (cetirizine) dose for your dog based on weight. Used for allergies, itching, and skin conditions with dosage chart.

Zyrtec for Dogs

Calculate the correct Zyrtec (cetirizine) dose for your dog based on weight. Used for allergies, itching, and skin conditions with dosage chart.

Dog's WeightEnter your dog's current weight

Tablet StrengthSelect the tablet strength you have

Use only plain cetirizine (Zyrtec). Do NOT use Zyrtec-D or any formulation containing pseudoephedrine or other decongestants, as these are toxic to dogs. Consult your veterinarian before starting any new medication.

Important Disclaimer

About This Calculator

Zyrtec (cetirizine) is a second-generation antihistamine that can be safely used in dogs for allergies, itching, and allergic skin conditions. Unlike first-generation antihistamines like Benadryl, cetirizine causes less drowsiness while still providing effective allergy relief.

How It Works

Zyrtec dosing for dogs is simplified: dogs under 10 lbs get 5mg once daily, and dogs over 10 lbs get 10mg once daily. This calculator confirms the appropriate dose based on your dog's weight and helps determine how many tablets to give.

Frequently Asked Questions

Yes, plain cetirizine (Zyrtec) tablets are safe for dogs. However, NEVER use Zyrtec-D or any formulation containing pseudoephedrine or decongestants, as these are toxic to dogs. Always check the ingredients.

Clinical Review

Dr. Igor I. Bussel, MD

Board-Certified Ophthalmologist

Dr. Igor I. Bussel is a board-certified ophthalmologist and fellowship-trained surgeon affiliated with the University of California, Irvine (UCI), the Gavin Herbert Eye Institute, and the UCI School of Medicine.

Last Updated: 2025-01-05

Sources & Guidelines

Medically Reviewed

Evidence-Based

Updated 2025-01-05

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References

Reviewed by: Veterinary Clinical Review Team (DVM)

Last updated: 2025-01-05